Multi Floor Deployment (Power Node 2i)

Good afternoon,

I'm moving to a new 3 floor townhome and will be moving my Power Node 2i with me.   Currently I have it connected to two wire KEF speakers it the ceiling.    This worked well in the current 1 bedroom but will not in the new place.

I was planning on doing a similar set up for the main living area, however I'd also like to have sound on the next two stories as well.    I believe I can add 2-3 Pulse Speakers to accomplish this task.    My question is whether a speak 2 stories above the main unit would still work or if that is too far away?

Thanks!